Description

2,6,6-Trimethylbicyclo[3.1.1]heptane-3-thiol is a specialized organosulfur compound belonging to the class of thiolated terpenes, characterized by its unique bicyclic structure and a reactive thiol (-SH) group. This compound is valued for its potent organoleptic properties and its role as a versatile chiral building block in fine chemical synthesis. It is primarily sought by industries involved in the development of high-value flavor and fragrance ingredients, as well as advanced pharmaceutical intermediates.

Application

• Flavor & Fragrance (F&F) Industry: Serves as a key intermediate or character-impact compound for creating complex, naturalistic sulfurous, grapefruit, or tropical notes in perfumes, colognes, and high-end flavor formulations.
• Pharmaceutical Synthesis: Acts as a valuable chiral synthon for constructing complex molecular architectures in active pharmaceutical ingredient (API) development, leveraging its bicyclic scaffold and thiol functionality.
• Agrochemical Intermediates: Used in the research and synthesis of novel crop protection agents and pesticides, where its terpene-derived structure can contribute to specific biological activity.
• Advanced Material Science: Employed as a functional monomer or cross-linking agent in the synthesis of specialty polymers and resins with tailored properties.
• Organic Synthesis & Catalysis: Functions as a ligand precursor or a reagent in asymmetric synthesis and metal-catalyzed reactions due to its stereogenic centers and sulfur atom.

Basic Information

Product Name	2,6,6-Trimethylbicyclo[3.1.1]heptane-3-thiol
CAS No.	72361-41-2
Molecular Formula	C10H18S
Molecular Weight	170.31 g/mol
Synonyms	3-Thiol-2,6,6-trimethylbicyclo[3.1.1]heptane; Pinan-3-thiol; 3-Mercapto-2,6,6-trimethylbicyclo[3.1.1]heptane; 3-Thiolpinane; Pinane-3-thiol; (1R,2R,3S,5R)-2,6,6-Trimethylbicyclo[3.1.1]heptane-3-thiol (enantiomer); (1S,2S,3R,5S)-2,6,6-Trimethylbicyclo[3.1.1]heptane-3-thiol (enantiomer)
EINECS	Contact for details

Quality Control

Our 2,6,6-Trimethylbicyclo[3.1.1]heptane-3-thiol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for flavor, fragrance, and pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation, minimize headspace and exposure to air after opening.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% ee (specify enantiomer)
Specific Rotation	Reported per COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.