Description

2-(4-Ethylpiperazin-1-Yl)-4-Phenyl-Quinoline Dihydrochloride is a high-purity, functionalized quinoline derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical synthetic intermediate or building block for developing novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, process development, and the synthesis of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders and other conditions.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Reference Standard: Serves as a high-purity analytical standard for method development, quality control, and regulatory submissions in pharmaceutical manufacturing.
• Organic Synthesis: Valuable intermediate for constructing complex quinoline-based molecular architectures in academic and industrial laboratories.
• Biochemical Research: Potential use as a tool compound or probe for investigating biological pathways and enzyme interactions.

Basic Information

Product Name	2-(4-Ethylpiperazin-1-Yl)-4-Phenyl-Quinoline Dihydrochloride
CAS No.	72320-60-6
Molecular Formula	C21H24Cl2N3
Molecular Weight	389.34 g/mol
Synonyms	2-(4-Ethyl-1-piperazinyl)-4-phenylquinoline dihydrochloride; 4-Phenyl-2-(4-ethylpiperazin-1-yl)quinoline dihydrochloride; 2-(4-Ethylpiperazin-1-yl)-4-phenylquinoline dihydrochloride; 72320-60-6; 4-Phenyl-2-(4-ethyl-1-piperazinyl)quinoline dihydrochloride; Quinoline, 2-(4-ethyl-1-piperazinyl)-4-phenyl-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-(4-Ethylpiperazin-1-Yl)-4-Phenyl-Quinoline Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.