Description

Apovincaminic Acid Hydrochloride Salt is a high-purity pharmaceutical intermediate and reference standard. This compound is critical for research and development in neuropharmacology and for the synthesis of advanced active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical manufacturers, biotechnology research firms, and academic institutions focused on developing treatments for cognitive disorders and improving cerebral circulation.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of vincamine alkaloid derivatives and related nootropic agents.
• Reference Standard: Used for analytical method development, validation, and quality control (QC/QA) in pharmaceutical laboratories.
• Neuropharmacology Research: Employed in preclinical studies investigating compounds for cerebral vasodilation and cognitive enhancement.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the manufacturing of finished dosage forms targeting cerebrovascular insufficiency.
• Biochemical Research: Utilized in studies exploring the mechanism of action of vinca alkaloids on neuronal cells and blood flow.

Basic Information

Product Name	Apovincaminic Acid Hydrochloride Salt
CAS No.	72296-47-0
Molecular Formula	C21H26N2O2 • HCl
Molecular Weight	374.91 g/mol
Synonyms	Apovincaminic Acid HCl; Apovincaminic Acid Hydrochloride; (3α,16α)-Eburnamenine-14-carboxylic Acid Hydrochloride; Vincaminic Acid Impurity; Apovincamine-14-carboxylic Acid Hydrochloride; Eburnamenine-14-carboxylic Acid Hydrochloride; 14-Carboxyapovincamine Hydrochloride
EINECS	Contact for details

Quality Control

Our Apovincaminic Acid Hydrochloride Salt is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical research and development. Certificates of Analysis (COA) documenting all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.