Description

3,5,8-Trioxabicyclo[2.2.2]Octane-1-Methanol is a specialized heterocyclic compound featuring a bicyclic acetal structure with a pendant hydroxymethyl group. This unique molecular architecture makes it a valuable intermediate and building block in advanced organic synthesis, particularly for creating complex, functionalized molecules. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and specialty polymer industries for applications requiring precise chemical modification and controlled reactivity.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those requiring complex, oxygen-rich heterocyclic scaffolds for improved solubility or bioactivity.
• Agrochemical Synthesis: Serves as a key building block for developing advanced herbicides, fungicides, and plant growth regulators with specific mode-of-action properties.
• Polymer & Resin Modifier: Acts as a cross-linking agent or functional monomer to introduce acetal linkages and hydroxyl functionality into specialty polymers, enhancing properties like adhesion, chemical resistance, or degradability.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to create novel chelating ligands for catalysis and material science applications.
• Chemical Research (R&D): A versatile synthon in academic and industrial research for exploring new synthetic methodologies and constructing complex molecular architectures.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value fine chemicals and flavors & fragrances where its specific reactivity is advantageous.

Basic Information

Product Name	3,5,8-Trioxabicyclo[2.2.2]Octane-1-Methanol
CAS No.	72252-47-2
Molecular Formula	C7H12O4
Molecular Weight	160.17 g/mol
Synonyms	1-(Hydroxymethyl)-3,5,8-trioxabicyclo[2.2.2]octane; 3,5,8-Trioxabicyclo[2.2.2]octane-1-methanol; 1-Hydroxymethyl-3,5,8-trioxabicyclo[2.2.2]octane; Bicyclo[2.2.2]octane-1-methanol, 3,5,8-trioxa-; 1,4-Dioxane-2,5-dimethanol, cyclic acetal with formaldehyde; Formaldehyde cyclic acetal with 1,4-dioxane-2,5-dimethanol
EINECS	Contact for details

Quality Control

Our 3,5,8-Trioxabicyclo[2.2.2]Octane-1-Methanol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.