Description

8-Hydroxynorcocaine is a key intermediate and metabolite in the study of cocaine and related tropane alkaloids. This compound is of significant value for pharmaceutical research and forensic analysis, providing critical insights into metabolic pathways and degradation products. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical developers working on neuropharmacology, toxicology, and biomarker discovery.

Application

• Pharmaceutical Research Intermediate: Serves as a critical synthetic precursor or reference standard in the development and study of tropane alkaloid derivatives.
• Forensic Toxicology: Used as a certified reference material (CRM) for the accurate identification and quantification of cocaine metabolites in biological samples.
• Metabolic Pathway Studies: Essential for in-vitro and in-vivo research to understand the biotransformation and pharmacokinetics of cocaine.
• Analytical Standard: Provides a high-purity benchmark for calibrating equipment like HPLC, LC-MS, and GC-MS in analytical laboratories.
• Biomarker Development: Aids in the development of diagnostic assays and tests for substance abuse monitoring.
• Academic Research: Used in university and institutional labs for chemical, pharmacological, and biochemical research projects.

Basic Information

Product Name	8-Hydroxynorcocaine
CAS No.	72182-43-5
Molecular Formula	C16H19NO5
Molecular Weight	305.33 g/mol
Synonyms	8-Hydroxy-norcocaine; Norcocaine-8-ol; 3-(Benzoyloxy)-8-hydroxy-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester; Benzoylecgonine-8-ol derivative; Cocaine metabolite 8-OH-NC; 8-HNC
EINECS	Contact for details

Quality Control

Our 8-Hydroxynorcocaine is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research chemicals, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.