Description

1-(α-(4-Oxo-2-Phenyl-3,4-Dihydro-3-Quinazolinyl)Hydrocinnamoyl)-3- (o-Tolyl)-2-Thiourea is a sophisticated heterocyclic organic compound featuring a quinazolinone core linked to a thiourea moiety, representing a high-value chemical building block. This compound matters for its role as a key intermediate in advanced pharmaceutical research and fine chemical synthesis, where precise molecular architecture is critical. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Acts as an intermediate in the research and synthesis of new generation pesticides or herbicides with tailored biological activity.
• Chemical Biology Probe: Utilized in the development of molecular probes to study biological pathways and protein functions.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to create complex molecules for advanced material science or specialty chemical applications.
• Academic & Institutional R&D: Used in university and research institute laboratories for fundamental studies in organic chemistry and heterocyclic compound development.

Basic Information

Item	Detail
Product Name	1-(α-(4-Oxo-2-Phenyl-3,4-Dihydro-3-Quinazolinyl)Hydrocinnamoyl)-3- (o-Tolyl)-2-Thiourea
CAS No.	72045-81-9
Molecular Formula	C32H26N4O2S
Molecular Weight	530.64 g/mol
Synonyms	1-[α-(4-Oxo-2-phenyl-3,4-dihydroquinazolin-3-yl)hydrocinnamoyl]-3-(2-methylphenyl)thiourea; 3-[3-(2-Methylphenyl)thioureido]-3-oxo-2-(4-oxo-2-phenyl-3,4-dihydroquinazolin-3-yl)propylbenzene; N-[α-(4-Oxo-2-phenyl-3,4-dihydro-3-quinazolinyl)hydrocinnamoyl]-N'-(o-tolyl)thiourea; 1-(α-(4-Oxo-2-phenyl-3,4-dihydro-3-quinazolinyl)hydrocinnamoyl)-3-(2-methylphenyl)-2-thiourea; o-Tolyl derivative of quinazolinone thiourea
EINECS	Contact for details

Quality Control

Our 1-(α-(4-Oxo-2-Phenyl-3,4-Dihydro-3-Quinazolinyl)Hydrocinnamoyl)-3- (o-Tolyl)-2-Thiourea is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. Certificates of Analysis (COA) detailing all specification parameters are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; therefore, the container should be kept tightly sealed in a dry environment. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.