Description

1-(3-Methyl-2-(4-Oxo-2-Phenyl-3,4-Dihydro-3-Quinazolinyl)Butyryl)-3-(P-Tolyl)-2-Thiourea is a sophisticated heterocyclic organic compound featuring a quinazolinone core linked to a thiourea moiety. This complex structure makes it a valuable advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily sought after by R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules, particularly for drug discovery programs targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, especially those with quinazoline-based pharmacophores.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in academic and industrial R&D settings.
• Biochemical Tool Compound: Used in biochemical assays to study enzyme inhibition or receptor binding, aiding in the identification of new biological targets.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex, high-value specialty chemicals for advanced material science and agrochemical research.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1-(3-Methyl-2-(4-Oxo-2-Phenyl-3,4-Dihydro-3-Quinazolinyl)Butyryl)-3-(P-Tolyl)-2-Thiourea
CAS No.	72045-75-1
Molecular Formula	C27H26N4O2S
Molecular Weight	470.59 g/mol
Synonyms	1-[3-Methyl-2-(4-oxo-2-phenyl-3,4-dihydroquinazolin-3-yl)butanoyl]-3-(4-methylphenyl)thiourea; 3-(4-Methylphenyl)-1-[3-methyl-2-(4-oxo-2-phenyl-3,4-dihydroquinazolin-3-yl)butanoyl]thiourea; N-(4-Methylphenyl)-N'-[3-methyl-2-(4-oxo-2-phenyl-3,4-dihydroquinazolin-3-yl)butanoyl]thiourea; 72045-75-1; Quinazolinone thiourea derivative; p-Tolyl thiourea quinazolinone conjugate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.