Description

Boc-Val-Nhnh2 CAS NO 72039-28-2 is a protected amino acid derivative, specifically a valine-based hydrazide with a tert-butoxycarbonyl (Boc) protecting group. This compound is a crucial building block in the synthesis of complex peptides and other bioactive molecules, offering precise control over chemical reactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for drug discovery and process development.

Application

• Peptide Synthesis: Serves as a key intermediate in solid-phase and solution-phase peptide synthesis, particularly for introducing valine residues with orthogonal protection.
• Pharmaceutical Intermediates: Used in the research and development of active pharmaceutical ingredients (APIs) and prodrugs.
• Bioconjugation: The hydrazide functional group enables selective conjugation with aldehydes and ketones, useful for labeling proteins and creating antibody-drug conjugates (ADCs).
• Chemical Biology Research: Employed as a tool compound for studying enzyme inhibition and protein-protein interactions.
• Fine Chemical Production: Acts as a chiral synthon for the asymmetric synthesis of more complex organic molecules.

Basic Information

Product Name	Boc-Val-Nhnh2
CAS No.	72039-28-2
Molecular Formula	C11H23N3O3
Molecular Weight	245.32 g/mol
Synonyms	Boc-Valine Hydrazide; N-(tert-Butoxycarbonyl)-L-valine hydrazide; (2S)-2-[(tert-Butoxycarbonyl)amino]-3-methylbutanehydrazide; tert-Butyl N-[(2S)-1-hydrazinyl-3-methyl-1-oxobutan-2-yl]carbamate; Boc-L-Val-NHNH2; BOC-VAL-NHNH2; Boc-Val-NHNH2
EINECS	Contact for details

Quality Control

Our Boc-Val-Nhnh2 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with high-grade standards for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.