Description

3,4,5-Trimethoxycinnamic Acid Anhydride is a high-purity, functionalized anhydride derivative of trimethoxycinnamic acid, serving as a versatile and reactive synthetic intermediate. Its value lies in providing a protected, activated carboxyl group that facilitates efficient coupling reactions under mild conditions, enabling the synthesis of complex molecules with high regioselectivity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for constructing bioactive scaffolds, natural product analogs, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, including potential anticancer, anti-inflammatory, and neuroprotective agents.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and plant growth regulators leveraging the cinnamate moiety.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and UV-absorbing compounds due to its conjugated aromatic system.
• Polymer & Material Science: Employed in the creation of specialty polyimides, epoxy resins, and other high-performance polymers requiring thermally stable and functional monomers.
• Bioconjugation & Probe Development: Useful in biochemical research for labeling proteins or creating fluorescent probes via reaction with amine groups.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry research.

Basic Information

Product Name	3,4,5-Trimethoxycinnamic Acid Anhydride
CAS No.	71989-97-4
Molecular Formula	C24H26O10
Molecular Weight	474.46 g/mol
Synonyms	3,4,5-Trimethoxycinnamic Anhydride; 3,4,5-Trimethoxycinnamic Acid Cyclic Anhydride; 2,5-Bis(3,4,5-trimethoxycinnamoyl)oxy)-3,4,5-trimethoxybenzoic acid (cyclic form); Cinnamic acid, 3,4,5-trimethoxy-, anhydride; Trimethoxycinnamic anhydride; (3,4,5-Trimethoxyphenyl)acrylic anhydride; 3,4,5-Trimethoxycinnamoyl anhydride
EINECS	Contact for details

Quality Control

Our 3,4,5-Trimethoxycinnamic Acid Anhydride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and loss on drying for moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.