Description

7,12-Dimethylbenz(A)Anthracene-3,4-Diol is a high-purity, synthetic dihydrodiol derivative of a polycyclic aromatic hydrocarbon (PAH). This compound serves as a critical advanced intermediate or reference standard in biochemical and toxicological research. It is primarily required by research institutions, pharmaceutical R&D labs, and analytical service providers for studies involving metabolic pathways, carcinogenesis, and DNA adduct formation.

Application

• Biochemical Research: Used as a metabolite standard in studies of PAH (polycyclic aromatic hydrocarbon) activation and detoxification pathways.
• Toxicology Studies: Serves as a key intermediate for investigating the mechanisms of chemical carcinogenesis and mutagenicity.
• Analytical Reference Standard: Employed in HPLC, GC-MS, and other analytical methods for the identification and quantification of PAH metabolites in complex matrices.
• Enzymology Research: Utilized as a substrate or inhibitor in studies of cytochrome P450 and epoxide hydrolase enzyme activities.
• Pharmaceutical Development: Acts as a building block or a tool compound in early-stage drug discovery programs targeting specific metabolic enzymes.
• Environmental Analysis: Applied in method development for monitoring human exposure to carcinogenic PAHs through biomarker analysis.

Basic Information

Product Name	7,12-Dimethylbenz(A)Anthracene-3,4-Diol
CAS No.	71964-72-2
Molecular Formula	C₂₀H₁₆O₂
Molecular Weight	288.34 g/mol
Synonyms	DMBA-3,4-diol; 3,4-Dihydroxy-7,12-dimethylbenz[a]anthracene; 7,12-DMBA-3,4-dihydrodiol; Benz[a]anthracene-3,4-diol, 7,12-dimethyl-; 7,12-Dimethylbenz[a]anthracene-3,4-dihydrodiol; (±)-7,12-Dimethylbenz[a]anthracene-3,4-diol; 3,4-Dihydroxy-7,12-DMBA
EINECS	Contact for details

Quality Control

Our 7,12-Dimethylbenz(A)Anthracene-3,4-Diol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data upon request, supporting research reproducibility and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.