Description

L-Tryptophan Isopropyl Ester Hydroc is a protected derivative of the essential amino acid L-Tryptophan, where the carboxylic acid group is esterified with isopropanol. This modification enhances its lipophilicity and stability, making it a crucial synthetic intermediate in advanced organic and medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical companies for the development of novel peptides, peptidomimetics, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate the tryptophan moiety while protecting the carboxylic acid functionality.
• Biochemical Research: Serves as a precursor in metabolic pathway studies and the development of enzyme inhibitors.
• Prodrug Development: The ester group can be utilized in prodrug strategies to improve the bioavailability of tryptophan-derived therapeutics.
• Fine Chemical Synthesis: Intermediate for creating complex organic molecules, including natural product analogs and specialty chemicals.

Basic Information

Product Name	L-Tryptophan Isopropyl Ester Hydroc
CAS No.	71959-71-2
Molecular Formula	C₁₄H₁₈N₂O₂
Molecular Weight	246.31 g/mol
Synonyms	L-Tryptophan isopropyl ester; (S)-2-Amino-3-(1H-indol-3-yl)propanoic acid isopropyl ester; Isopropyl L-tryptophanate; Tryptophan isopropyl ester; H-Trp-OiPr; Fmoc-Trp(Boc)-OH isopropyl ester (protected form); Tryptophan isopropylester; L-α-Amino-1H-indole-3-propanoic acid 1-methylethyl ester
EINECS	Contact for details

Quality Control

Our L-Tryptophan Isopropyl Ester Hydroc is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	-30.0° to -34.0° (c=1 in methanol)
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.