Description

Proline, 1-Nitroso-, Methyl Ester (9Ci) is a specialized nitrosated proline derivative, a key intermediate in advanced organic synthesis and pharmaceutical research. Its value lies in its unique molecular structure, which serves as a versatile building block for constructing complex nitrogen-containing heterocycles and bioactive molecules. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries, particularly for developing novel compounds and exploring new synthetic pathways. Its precise synthesis and high purity are critical for ensuring reproducible results in sensitive applications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Agrochemical Research: Used in developing new pesticides and herbicides by serving as a scaffold for nitrogen-rich active ingredients.
• Fine Chemical Synthesis: Acts as a specialized building block for creating complex chiral molecules and custom-designed ligands for catalysis.
• Bioconjugation & Probe Development: Utilized in biochemical research for modifying peptides and proteins, or creating fluorescent or affinity probes.
• Academic & Industrial R&D: Serves as a key reagent in methodological studies and the exploration of new nitrosation and cyclization reactions.
• Material Science Precursor: Potential use in synthesizing organic frameworks or polymers with specific functional properties.

Basic Information

Item	Details
Product Name	Proline, 1-Nitroso-, Methyl Ester (9Ci)
CAS No.	71922-04-8
Molecular Formula	C6H10N2O3
Molecular Weight	158.16 g/mol
Synonyms	1-Nitroso-L-proline methyl ester; Methyl 1-nitroso-L-prolinate; Methyl 1-nitrosoproline-2-carboxylate; L-Proline, 1-nitroso-, methyl ester; (S)-1-Nitroso-pyrrolidine-2-carboxylic acid methyl ester; 1-Nitroso-proline methyl ester; Proline, 1-nitroso-, methyl ester (9CI)
EINECS	Contact for details

Quality Control

Our Proline, 1-Nitroso-, Methyl Ester (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, spectroscopic identification (IR, NMR), and determination of residual solvents and moisture content. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	Light yellow to yellow solid or oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.