Description

1,5-Dioxa-9-Aza-Spiro[5.5]Undecane, Hydrochloride is a versatile spirocyclic building block and heterocyclic compound of significant interest in advanced organic synthesis. Its unique bridged structure containing both ether and amine functionalities makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those requiring rigid, three-dimensional scaffolds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where its spirocyclic core can contribute to unique biological activity.
• Ligand and Catalyst Synthesis: Employed for constructing chelating ligands or organocatalysts due to the presence of nitrogen and oxygen donor atoms within a constrained geometry.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal or mechanical properties.
• Chemical Biology Probes: Useful for creating molecular probes and tools to study biological processes, leveraging its ability to be further functionalized.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical spaces in synthetic organic chemistry laboratories.

Basic Information

Product Name	1,5-Dioxa-9-Aza-Spiro[5.5]Undecane, Hydrochloride
CAS No.	71879-41-9
Molecular Formula	C8H15NO2 • HCl
Molecular Weight	193.67 g/mol (Free base: 157.21 g/mol)
Synonyms	9-Aza-1,5-dioxaspiro[5.5]undecane hydrochloride; 1,5-Dioxa-9-azaspiro[5.5]undecane hydrochloride; Spiro(1,3-dioxane-5,3'-piperidine) hydrochloride; 3,9-Dioxa-7-azaspiro[5.5]undecane hydrochloride (alternative numbering); Aza-crown ether analog hydrochloride; Spirocyclic amino ether hydrochloride
EINECS	Contact for details

Quality Control

Our 1,5-Dioxa-9-Aza-Spiro[5.5]Undecane, Hydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and titration to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.