Description

Piperazine Hydroiodide is a versatile organic salt formed from piperazine and hydroiodic acid, serving as a critical reagent and intermediate in advanced chemical synthesis. Its value lies in providing a stable, readily available source of both the piperazine moiety and iodide ion for demanding pharmaceutical and research applications. This compound is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and specialty chemical sectors, where precise molecular construction is paramount.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing piperazine rings, such as certain anthelmintics, antidepressants, and antipsychotics.
• Organic Synthesis Reagent: Acts as a source of piperazine for nucleophilic substitution reactions and as an iodide source in halogenation or catalyst systems in research and process chemistry.
• Agrochemical Synthesis: Used in the production of certain fungicides, herbicides, and plant growth regulators that incorporate the piperazine structure.
• Chemical Research: Employed in academic and industrial laboratories for method development, catalysis studies, and the preparation of novel chemical entities.
• Complexing Agent: Can function in the preparation of metal complexes or coordination polymers for material science applications.

Basic Information

Product Name	Piperazine Hydroiodide
CAS No.	71850-05-0
Molecular Formula	C₄H₁₂N₂•HI
Molecular Weight	232.07 g/mol
Synonyms	Piperazine Hydroiodide; Piperazine, hydroiodide (1:1); Piperazinium iodide; 1,4-Diazacyclohexane hydroiodide; Piperazine monohydroiodide; Piperazine HI salt; Piperazine hydriodide; Piperazine-2HCl (common mis-identification, included for clarity)
EINECS	Contact for details

Quality Control

Our Piperazine Hydroiodide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and impurity profiles. We provide Certificates of Analysis (COA) with each shipment, detailing results for key parameters such as assay, related substances, and residual solvents. Our quality commitment supports applications requiring high-purity intermediates, including cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect product stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.