Description

Di-p-Toluoyl-D-Tartaric Acid Monohydrate is a high-purity chiral resolving agent and synthetic intermediate of significant importance in asymmetric synthesis. Its primary value lies in its ability to separate enantiomers of chiral amines and other compounds, a critical process in pharmaceutical development. This product is essential for research laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the production of single-enantiomer active pharmaceutical ingredients (APIs).

Application

• As a chiral resolving agent for the optical resolution of racemic amines, amino alcohols, and other basic pharmaceuticals.
• As a key chiral auxiliary or catalyst precursor in asymmetric synthesis and stereoselective transformations.
• In the research and development of enantiomerically pure compounds for pharmaceutical and agrochemical applications.
• For the preparation of chiral stationary phases (CSPs) used in high-performance liquid chromatography (HPLC) for analytical separation.
• As a building block in the synthesis of more complex chiral ligands and organocatalysts.
• In quality control laboratories for the chiral purity analysis of pharmaceutical intermediates and final products.

Basic Information

Product Name	Di-p-Toluoyl-D-Tartaric Acid Monohydrate
CAS No.	71607-31-3
Molecular Formula	C20H20O9 • H2O
Molecular Weight	416.38 g/mol (Anhydrous basis: 398.37)
Synonyms	(2R,3R)-2,3-Bis(4-methylbenzoyloxy)succinic acid monohydrate; D-(-)-Di-p-Toluoyltartaric Acid Monohydrate; D-DTTA Monohydrate; (R,R)-DIPT Monohydrate; D-(-)-Di-p-Toluoyltartaric Acid Hydrate; (2R,3R)-2,3-Di-(p-toluoyloxy)succinic Acid Monohydrate; (R,R)-Di-p-Toluoyl Tartaric Acid Monohydrate; L-(+)-Tartaric Acid Di-p-methylbenzoate Monohydrate (enantiomer)
EINECS	Contact for details

Quality Control

Our Di-p-Toluoyl-D-Tartaric Acid Monohydrate is manufactured under controlled conditions to ensure consistent high quality suitable for demanding applications like chiral resolution and asymmetric synthesis. Each batch undergoes rigorous analytical testing, including chiral purity assay by HPLC and identification by spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which may affect performance and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Water Content (KF)	3.5 - 5.5% (Theoretical for monohydrate: ~4.3%)
Specific Rotation [α]D20	-120° to -130° (c=1 in acetone)
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.