Description

2-Cyclobutyl-1-Phenylquinazolin-4(1H)-One is a specialized quinazolinone derivative, a heterocyclic scaffold of significant interest in advanced organic synthesis. This compound matters as a versatile and high-value chemical building block for research and development, particularly in the pharmaceutical sector. It is primarily needed by R&D chemists and process development scientists in pharmaceutical, agrochemical, and material science industries for creating novel active molecules and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other biological pathways where the quinazolinone core is active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Acts as a potential electron-transport or host material in the fabrication of OLED devices due to its rigid, conjugated structure.
• Coordination Chemistry & Ligand Synthesis: The nitrogen atoms in the quinazolinone ring can coordinate to metal centers, making it useful for creating novel catalysts or metal-organic frameworks (MOFs).
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for methodological studies and exploring new chemical reactions.
• Fluorescent Probe Development: Utilized in the design of fluorescent dyes or sensors for biological or chemical detection applications.

Basic Information

Product Name	2-Cyclobutyl-1-Phenylquinazolin-4(1H)-One
CAS No.	71567-80-1
Molecular Formula	C18H16N2O
Molecular Weight	276.34 g/mol
Synonyms	4(1H)-Quinazolinone, 2-cyclobutyl-1-phenyl-; 1-Phenyl-2-cyclobutyl-1,4-dihydroquinazolin-4-one; 2-Cyclobutyl-1-phenyl-1,4-dihydroquinazolin-4-one; 2-Cyclobutyl-1-phenylquinazolin-4-ol; 2-Cyclobutyl-1-phenyl-4(1H)-quinazolinone
EINECS	Contact for details

Quality Control

Our 2-Cyclobutyl-1-Phenylquinazolin-4(1H)-One is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports cGMP and ISO standards for reliable integration into critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.