Description

Disialyl Galactosyl Biantennary Glycan (A2) is a complex, biantennary N-linked oligosaccharide featuring terminal sialic acid residues. This highly defined glycan structure is critical for studying and replicating the biological activity of glycoproteins, particularly in the context of cell-cell recognition and signaling. It serves as an essential reference standard and building block for researchers and manufacturers in the biopharmaceutical and diagnostic sectors who require precise glycan analysis and conjugation.

Application

• Biopharmaceutical Reference Standard: Used for the identification, qualification, and quantification of glycans in therapeutic proteins like monoclonal antibodies and recombinant hormones.
• Glycan Array and Diagnostic Development: Acts as a key ligand for profiling antibody and lectin specificity in high-throughput screening platforms and diagnostic assay development.
• Glycoengineering Research: Serves as a critical substrate or target structure for studying glycosyltransferase and glycosidase enzyme activity in pathway engineering.
• Cell Biology Studies: Utilized in research on cell adhesion, immune response modulation, and pathogen-host interactions mediated by sialylated glycans.
• Conjugate Vaccine Development: Employed as a well-defined hapten for coupling to carrier proteins to develop more consistent and immunogenic carbohydrate-based vaccines.
• Quality Control in Biologics Manufacturing: Essential for monitoring and ensuring batch-to-batch consistency of glycosylation patterns, a critical quality attribute for biologic drugs.

Basic Information

Product Name	Disialyl Galactosyl Biantennary Glycan (A2)
CAS No.	71496-55-4
Molecular Formula	C94H153N5O71
Molecular Weight	2440.2 g/mol (theoretical)
Synonyms	A2 Glycan; Biantennary Disialylated N-Glycan; Disialylated Biantennary N-Glycan; NGA2; NA2; Disialo-Biantennary N-Glycan; Asialo-A2 (reduced form); A2G2S2; 2,6-Sialyl Lactosamine Biantennary N-Glycan
EINECS	Contact for details

Quality Control

Our Disialyl Galactosyl Biantennary Glycan (A2) is produced and tested to meet the stringent requirements of research and biopharmaceutical applications. Each batch is characterized using advanced analytical techniques including HPLC, MS, and NMR to confirm structural identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided to ensure full traceability and compliance with your quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Bacterial Endotoxins	< 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.