Description

[3-(tert-Butoxycarbonylamino-Methyl)-Phenyl]-Acetic Acid is a high-purity, protected amino acid derivative of significant value in advanced organic synthesis. This compound serves as a critical building block for the construction of complex molecules, offering a versatile handle for further functionalization. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptides, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a protected amino acid derivative for the solid-phase or solution-phase synthesis of peptides and peptidomimetics.
• Linker Molecule: Employed in bioconjugation and the development of antibody-drug conjugates (ADCs) due to its reactive carboxylic acid and protected amine functionalities.
• Chemical Biology Research: Serves as a valuable tool compound for probing biological pathways and developing enzyme inhibitors or receptor modulators.
• Material Science: Can be utilized in the synthesis of specialized polymers or functionalized surfaces requiring specific organic moieties.
• Custom Synthesis: Acts as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	[3-(tert-Butoxycarbonylamino-Methyl)-Phenyl]-Acetic Acid
CAS No.	71420-95-6
Molecular Formula	C15H21NO4
Molecular Weight	279.33 g/mol
Synonyms	Boc-AMPA; 3-[(tert-Butoxycarbonylamino)methyl]phenylacetic acid; N-Boc-3-(aminomethyl)phenylacetic acid; 2-[3-[[(2-Methylpropan-2-yl)oxycarbonylamino]methyl]phenyl]acetic acid; (3-{[(tert-Butoxycarbonyl)amino]methyl}phenyl)acetic acid; N-(tert-Butoxycarbonyl)-3-(aminomethyl)phenylacetic acid; Boc-3-Ampa
EINECS	Contact for details

Quality Control

Our [3-(tert-Butoxycarbonylamino-Methyl)-Phenyl]-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.