Description

4-Boc-Aminomethylphenylacetic Acid is a protected amino acid derivative of significant importance in advanced organic synthesis. This compound serves as a crucial building block for the construction of complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by pharmaceutical intermediates manufacturers and research institutions focused on peptide chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Peptide Synthesis: Used as a protected amino acid component in solid-phase and solution-phase peptide synthesis.
• Protease Inhibitor Development: Serves as a scaffold for designing enzyme inhibitors targeting various proteases.
• Linker Chemistry: Employed in the creation of chemical linkers for bioconjugation and prodrug strategies.
• Chemical Biology Research: Utilized in the synthesis of probes and tools for studying biological processes.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs for custom molecule fabrication.

Basic Information

Product Name	4-Boc-Aminomethylphenylacetic Acid
CAS No.	71420-92-3
Molecular Formula	C₁₄H₁₉NO₄
Molecular Weight	265.31 g/mol
Synonyms	4-[[(1,1-Dimethylethoxy)carbonyl]amino]methyl]benzeneacetic Acid; 4-(Boc-aminomethyl)phenylacetic Acid; N-Boc-4-aminomethylphenylacetic Acid; (4-((tert-Butoxycarbonylamino)methyl)phenyl)acetic Acid; 2-[4-[(tert-Butoxycarbonylamino)methyl]phenyl]acetic Acid; Boc-Ampa-OH; Boc-4-Ampa-OH
EINECS	Contact for details

Quality Control

Our 4-Boc-Aminomethylphenylacetic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.