Description

Hydracrylic Acid, 3-(4-Biphenylyl)-3-(p-Bromophenyl)-, (+)- is a high-purity, single-enantiomer chiral compound with a complex biphenyl-bromophenyl core structure. This compound is valued for its role as a critical chiral intermediate in advanced organic synthesis, enabling the production of enantiomerically pure pharmaceuticals and specialty chemicals. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug research.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced functional materials used in display technologies due to its rigid, substituted biphenyl structure.
• Asymmetric Catalysis Ligand Precursor: Employed in the synthesis of chiral ligands for asymmetric hydrogenation and C-C bond formation reactions.
• Academic & Industrial R&D: A valuable tool for chemists in universities and corporate labs exploring new synthetic methodologies and structure-activity relationships.
• Fine Chemical Production: Used in the multi-step synthesis of other high-value, complex chiral molecules for various specialty applications.

Basic Information

Product Name	Hydracrylic Acid, 3-(4-Biphenylyl)-3-(p-Bromophenyl)-, (+)-
CAS No.	71315-11-2
Molecular Formula	C21H17BrO3
Molecular Weight	397.26 g/mol
Synonyms	(+)-3-(4-Biphenylyl)-3-(4-bromophenyl)hydracrylic acid; (R)-3-([1,1'-Biphenyl]-4-yl)-3-(4-bromophenyl)propanoic acid; (3R)-3,3-Bis(4-phenylphenyl)-2-hydroxypropanoic acid (p-bromo derivative); Biphenyl-bromophenyl hydracrylic acid; Chiral biphenyl propanoic acid derivative; BPHPA; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our production of Hydracrylic Acid, 3-(4-Biphenylyl)-3-(p-Bromophenyl)-, (+)- adheres to stringent in-process controls to ensure batch-to-batch consistency and high enantiomeric purity. Every lot is fully characterized using advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with each shipment, supporting cGMP and ISO 9001 compliant workflows for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.