Description

Phenol, 5-(Aminomethyl)-2,4-Difluoro- (9Ci) is a specialized fluorinated phenol derivative featuring an aminomethyl functional group, making it a versatile building block for advanced synthesis. This compound is valued for its unique molecular architecture, which allows for the introduction of both fluorine atoms and a reactive amine handle into target molecules. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in areas like kinase inhibitors, CNS agents, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the difluorophenol moiety enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, resins, and advanced materials requiring fluorinated aromatic components.
• Chemical Biology Probes: Useful for constructing fluorescent tags, affinity labels, and other molecular probes due to its reactive amine group for conjugation.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Phenol, 5-(Aminomethyl)-2,4-Difluoro- (9Ci)
CAS No.	71288-97-6
Molecular Formula	C7H7F2NO
Molecular Weight	159.13 g/mol
Synonyms	5-(Aminomethyl)-2,4-difluorophenol; 2,4-Difluoro-5-(aminomethyl)phenol; 2,4-Difluoro-5-(aminomethyl)phenol (9CI); 5-(Aminomethyl)-2,4-difluoro-phenol; 3-Aminomethyl-4,6-difluorophenol; (3-Aminomethyl-4,6-difluoro)phenol; 4,6-Difluoro-3-(aminomethyl)phenol
EINECS	Contact for details

Quality Control

Every batch of Phenol, 5-(Aminomethyl)-2,4-Difluoro- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and process chemistry. A detailed Certificate of Analysis (COA) including purity (HPLC), identity confirmation (IR, NMR), and impurity profile is supplied with each shipment to guarantee reproducible performance and supply chain reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.