Description

Propanoic Acid, 2-[[(4-Methylphenyl)Sulfonyl]Oxy]-, Methyl Ester, (S)- is a high-purity chiral sulfonate ester derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile chiral intermediate, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals with high stereoselectivity. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and complex molecular architectures.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A critical precursor for the development of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other targeted therapies.
• Agrochemical Research & Development: Used in the synthesis of novel, stereospecific herbicides, fungicides, and plant growth regulators.
• Asymmetric Catalysis & Ligand Synthesis: Serves as a starting material for the preparation of chiral ligands and catalysts used in stereoselective transformations.
• Fine Chemical and Specialty Polymer Production: Employed in the manufacture of high-value fine chemicals and as a monomer or modifier in specialty polymers requiring specific chiral centers.
• Academic and Industrial R&D: A valuable tool for methodological development in organic chemistry and for exploring new synthetic routes in process chemistry.

Basic Information

Product Name	Propanoic Acid, 2-[[(4-Methylphenyl)Sulfonyl]Oxy]-, Methyl Ester, (S)-
CAS No.	71283-66-4
Molecular Formula	C12H16O5S
Molecular Weight	272.32 g/mol
Synonyms	(S)-Methyl 2-[(4-toluenesulfonyl)oxy]propanoate; (S)-Methyl 2-[(p-tolylsulfonyl)oxy]propionate; (S)-Methyl 2-((4-methylphenyl)sulfonyloxy)propanoate; (S)-Methyl 2-(tosyloxy)propanoate; (S)-Methyl lactate tosylate; L-Lactic acid methyl ester tosylate; (S)-2-(p-Toluenesulfonyloxy)propionic acid methyl ester; Methyl (S)-2-((4-methylphenyl)sulfonyloxy)propanoate
EINECS	Contact for details

Quality Control

Our Propanoic Acid, 2-[[(4-Methylphenyl)Sulfonyl]Oxy]-, Methyl Ester, (S)- is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity (enantiomeric excess), chemical purity (HPLC), and identity confirmation. We support development and commercial projects requiring material that meets stringent ICH guidelines for impurities and stability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.