Description

n-(3-Trifluoromethyl-Phenyl)-Guanidine is a specialized guanidine derivative featuring a trifluoromethylphenyl substituent, which imparts unique electronic and steric properties. This compound is valued for its role as a versatile building block and intermediate in advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It is essential for researchers and manufacturers in fine chemical, pharmaceutical R&D, and crop protection industries seeking to introduce guanidine functionality into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, kinase inhibitors, and antiviral agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, resins, and coatings with tailored properties.
• Chemical Biology & Proteomics: Employed as a tool compound or a scaffold for designing enzyme inhibitors and molecular probes due to its strong hydrogen-bonding capability.
• Dye & Pigment Industry: Acts as an intermediate in the production of advanced colorants and functional dyes.

Basic Information

Product Name	n-(3-Trifluoromethyl-Phenyl)-Guanidine
CAS No.	71198-37-3
Molecular Formula	C8H8F3N3
Molecular Weight	203.16 g/mol
Synonyms	1-[3-(Trifluoromethyl)phenyl]guanidine; N-[3-(Trifluoromethyl)phenyl]guanidine; 3-(Trifluoromethyl)phenylguanidine; m-Trifluoromethylphenylguanidine; Guanidine, N-[3-(trifluoromethyl)phenyl]-; 3-Trifluoromethylphenylguanidine; (3-Trifluoromethylphenyl)guanidine
EINECS	Contact for details

Quality Control

Our n-(3-Trifluoromethyl-Phenyl)-Guanidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) documenting all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.