Description

1-(Methylsulfonyl)-1,2,3,4-Tetrahydroquinoline is a high-purity organic building block featuring a tetrahydroquinoline core functionalized with a methylsulfonyl group. This compound matters as a versatile and valuable intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, contributing to novel modes of action.
• Material Science Research: Serves as a precursor for functionalized polymers and advanced organic materials with specific electronic properties.
• Chemical Biology & Proteomics: Can be utilized as a building block for activity-based probes or affinity tags to study enzyme function.
• Catalyst & Ligand Development: Employed in the synthesis of novel chiral ligands or organocatalysts for asymmetric synthesis.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	1-(Methylsulfonyl)-1,2,3,4-Tetrahydroquinoline
CAS No.	71173-39-2
Molecular Formula	C10H13NO2S
Molecular Weight	211.28 g/mol
Synonyms	1-(Methylsulfonyl)-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-1-(methylsulfonyl)quinoline; N-(Methylsulfonyl)-1,2,3,4-tetrahydroquinoline; Quinoline, 1,2,3,4-tetrahydro-1-(methylsulfonyl)-; 1-Methanesulfonyl-1,2,3,4-tetrahydroquinoline; MS-THQ
EINECS	Contact for details

Quality Control

Our 1-(Methylsulfonyl)-1,2,3,4-Tetrahydroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.