Description

6-Fluoro-4-Hydroxyquinoline-3- Carbonitrile is a high-value, multifunctional heterocyclic building block. This compound is critical for the synthesis of advanced pharmaceutical intermediates and fine chemicals due to its reactive nitrile and hydroxyl groups on the quinoline scaffold. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating novel active molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antibacterial agents, and other bioactive quinoline derivatives.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its fluorine-substituted quinoline structure.
• Material Science: Serves as a building block for organic semiconductors, ligands for metal complexes, and fluorescent dyes.
• Chemical Synthesis: Employed in organic synthesis for constructing complex heterocyclic systems via its versatile functional groups.
• Academic & Contract Research: Utilized in university and CRO laboratories for medicinal chemistry programs and novel compound library generation.

Basic Information

Product Name	6-Fluoro-4-Hydroxyquinoline-3-Carbonitrile
CAS No.	71083-60-8
Molecular Formula	C₁₀H₅FN₂O
Molecular Weight	188.16 g/mol
Synonyms	6-Fluoro-4-hydroxy-3-quinolinecarbonitrile; 4-Hydroxy-6-fluoroquinoline-3-carbonitrile; 3-Cyano-6-fluoro-4-hydroxyquinoline; 6-Fluoro-4-hydroxyquinoline-3-carbonitrile; 6-Fluoro-4-oxo-1,4-dihydroquinoline-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Fluoro-4-Hydroxyquinoline-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.