Description

6,8-Difluoro-3-Quinolinecarbonitrile is a high-purity fluorinated quinoline derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex molecules with tailored biological and material properties. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antimicrobial agents, and other biologically active heterocyclic compounds.
• Agrochemical Synthesis: Used in the research and production of next-generation pesticides and herbicides, where the difluoroquinoline core contributes to enhanced efficacy and environmental profile.
• Material Science Research: Serves as a precursor for the development of organic electronic materials, such as ligands for OLEDs or components for molecular sensors, due to its electron-deficient quinoline structure.
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent tags or molecular probes for studying biological processes and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes requiring high-purity fluorinated intermediates.

Basic Information

Product Name	6,8-Difluoro-3-Quinolinecarbonitrile
CAS No.	71083-55-1
Molecular Formula	C10H4F2N2
Molecular Weight	190.15 g/mol
Synonyms	3-Cyano-6,8-difluoroquinoline; 6,8-Difluoroquinoline-3-carbonitrile; 6,8-Difluoro-3-cyanoquinoline; Quinoline-3-carbonitrile, 6,8-difluoro-; 71083-55-1; 6,8-Difluoro-3-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 6,8-Difluoro-3-Quinolinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.