Description

8-Fluoroquinoline-3-Carbonitrile CAS NO 71083-52-8 is a high-value, multi-functional heterocyclic building block characterized by its fluorinated quinoline core and reactive nitrile group. This compound is essential for advanced organic synthesis, enabling the efficient construction of complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for applications in medicinal chemistry, ligand design, and the development of novel functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antimicrobial research.
• Agrochemical Synthesis: Used in the creation of advanced active ingredients for crop protection products.
• Ligand and Catalyst Development: Serves as a precursor for constructing complex chelating ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, fluorescent dyes, and other functional organic materials.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study biological systems.
• Custom Synthesis and Contract Manufacturing: A critical starting material for bespoke chemical synthesis services.

Basic Information

Product Name	8-Fluoroquinoline-3-Carbonitrile
CAS No.	71083-52-8
Molecular Formula	C10H5FN2
Molecular Weight	172.16 g/mol
Synonyms	8-Fluoro-3-cyanoquinoline; 8-Fluoroquinoline-3-carbonitrile; 3-Cyano-8-fluoroquinoline; Quinoline-3-carbonitrile, 8-fluoro-; 8-Fluoro-3-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 8-Fluoroquinoline-3-Carbonitrile is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.