Description

6-Fluoroquinoline-3-Carbonitrile is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique molecular architecture, featuring both a fluorine substituent and a nitrile group on the quinoline core, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new fluorinated quinolone-based antibiotics and other bioactive molecules.
• Agrochemical Research: Used in the synthesis of advanced fungicides, herbicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for creating functionalized organic materials, such as ligands for catalysts or components for organic electronics.
• Chemical Biology Probe Development: Employed in the design and synthesis of fluorescent probes or molecular tags for biological imaging and diagnostic applications.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, particularly in cross-coupling and cyclization reactions.

Basic Information

Product Name	6-Fluoroquinoline-3-Carbonitrile
CAS No.	71083-44-8
Molecular Formula	C₁₀H₅FN₂
Molecular Weight	172.16 g/mol
Synonyms	6-Fluoro-3-cyanoquinoline; 6-Fluoroquinoline-3-carbonitrile; 3-Cyano-6-fluoroquinoline; Quinoline-3-carbonitrile, 6-fluoro-; 6-Fluoro-3-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 6-Fluoroquinoline-3-Carbonitrile is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.