Description

7-(Trifluoromethyl)Quinoline-3-Carboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block prized for its unique trifluoromethyl-substituted quinoline scaffold. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where the CF3 group imparts desirable properties like enhanced metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-infective research.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Used in the creation of organic semiconductors, ligands for catalysis, and fluorescent dyes.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes and diagnostic agents.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in academic and CRO laboratories.
• Scale-up & Process Chemistry: Supplied for route scouting and optimization during the transition from laboratory to pilot plant scale.

Basic Information

Product Name	7-(Trifluoromethyl)Quinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	71083-18-6
Molecular Formula	C13H10F3NO2
Molecular Weight	269.22 g/mol
Synonyms	Ethyl 7-(Trifluoromethyl)quinoline-3-carboxylate; 7-(Trifluoromethyl)-3-quinolinecarboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic acid, 7-(trifluoromethyl)-, ethyl ester; Ethyl 7-(trifluoromethyl)quinoline-3-carboxylate; 7-Trifluoromethylquinoline-3-carboxylic acid ethyl ester; Quinoline-3-carboxylic acid, 7-(trifluoromethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)Quinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.