Description

6-Fluoroquinoline-3-Carboxylic Acid Ethyl Ester is a high-value fluorinated quinoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the strategic fluorine atom and ester functionality, which enable precise molecular modifications for developing novel active compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating new active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel fluoroquinolone-based antibiotics and other bioactive molecules.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and stability.
• Material Science: Serves as a precursor for the synthesis of functionalized organic ligands and fluorinated organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions and as a scaffold for constructing complex heterocyclic compounds in medicinal chemistry.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting research in fluorochemistry and drug discovery.

Basic Information

Product Name	6-Fluoroquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	71083-14-2
Molecular Formula	C₁₂H₁₀FNO₂
Molecular Weight	219.21 g/mol
Synonyms	Ethyl 6-Fluoroquinoline-3-carboxylate; 6-Fluoro-3-quinolinecarboxylic Acid Ethyl Ester; 6-Fluoroquinoline-3-carboxylic Acid Ethyl Ester; 3-Carbethoxy-6-fluoroquinoline; Ethyl 6-fluoro-3-quinolinecarboxylate; 6-Fluoroquinoline-3-carboxylic acid, ethyl ester; 6-Fluoro-3-quinolinecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 6-Fluoroquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.