Description

Ethyl 1,4-Dihydro-8-Fluoro-4-Oxoquinoline-3-Carboxylate is a high-purity fluorinated quinoline derivative that serves as a critical advanced pharmaceutical intermediate. Its value lies in its role as a key building block for the synthesis of novel fluoroquinolone antibiotics and other bioactive molecules. This compound is essential for research and development laboratories, fine chemical manufacturers, and pharmaceutical companies focused on antimicrobial and anti-infective drug discovery.

Application

• Pharmaceutical Intermediate: Primary building block for synthesizing next-generation fluoroquinolone antibiotics.
• Antimicrobial Research: Core scaffold in medicinal chemistry for developing novel antibacterial and antifungal agents.
• Fine Chemical Synthesis: Key precursor in multi-step organic syntheses for complex heterocyclic compounds.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for GMP-scale API production.
• Academic & Industrial R&D: Used in research institutions for studying structure-activity relationships (SAR) of quinolone derivatives.
• Process Development: Employed in route scouting and optimization for scalable API manufacturing processes.

Basic Information

Product Name	Ethyl 1,4-Dihydro-8-Fluoro-4-Oxoquinoline-3-Carboxylate
CAS No.	71083-06-2
Molecular Formula	C₁₂H₁₀FNO₃
Molecular Weight	235.21 g/mol
Synonyms	Ethyl 8-Fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate; 8-Fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; 8-Fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Ethyl Ester; Ethyl 8-Fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate; 1,4-Dihydro-8-fluoro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; 8-Fluoro-4-oxoquinoline-3-carboxylic Acid Ethyl Ester; 8-Fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 1,4-Dihydro-8-Fluoro-4-Oxoquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to prevent degradation from moisture and light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.