Description

Ethyl4-Oxo-7-(Trifluoromethyl)-1,4-Dihydroquinoline-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its distinct quinoline core and trifluoromethyl substituent. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents with enhanced metabolic stability and bioavailability. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs), particularly in areas requiring fluorinated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Serves as a core structure for developing new generation pesticides and herbicides, leveraging the bioactivity of the quinoline moiety.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex fluorinated heterocyclic compounds for material science and chemical biology.
• Fluorine Chemistry Studies: An important compound for investigating structure-activity relationships (SAR) due to the presence of the pharmacologically valuable trifluoromethyl group.

Basic Information

Product Name	Ethyl4-Oxo-7-(Trifluoromethyl)-1,4-Dihydroquinoline-3-Carboxylate
CAS No.	71083-04-0
Molecular Formula	C₁₃H₁₀F₃NO₃
Molecular Weight	285.22 g/mol
Synonyms	Ethyl 7-(Trifluoromethyl)-4-oxo-1,4-dihydroquinoline-3-carboxylate; 7-(Trifluoromethyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid Ethyl Ester; 1,4-Dihydro-7-(trifluoromethyl)-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic acid, 1,4-dihydro-7-(trifluoromethyl)-4-oxo-, ethyl ester; Ethyl 1,4-dihydro-7-(trifluoromethyl)-4-oxoquinoline-3-carboxylate; CAS 71083-04-0
EINECS	Contact for details

Quality Control

Our Ethyl4-Oxo-7-(Trifluoromethyl)-1,4-Dihydroquinoline-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.