Description

4-Oxo-6-Trifluoromethyl-1,4-Dihydro-Quinoline-3-Carboxylic Acid Ethyl Ester is a high-value fluorinated quinoline derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the trifluoromethyl group, which imparts unique physicochemical properties essential for developing bioactive molecules. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on creating novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinolone and fluoroquinolone antibiotic candidates.
• Agrochemical Research: Precursor in developing advanced pesticides and herbicides, leveraging the bioactivity-enhancing CF3 group.
• Material Science: Used in the research and development of specialty polymers and organic electronic materials.
• Chemical Synthesis: Versatile scaffold for constructing complex heterocyclic compounds in medicinal and combinatorial chemistry.
• Fluorine Chemistry Studies: A valuable reference compound for studying the effects of fluorine substitution on molecular properties and reactivity.

Basic Information

Product Name	4-Oxo-6-Trifluoromethyl-1,4-Dihydro-Quinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	71083-01-7
Molecular Formula	C13H10F3NO3
Molecular Weight	285.22 g/mol
Synonyms	Ethyl 6-(trifluoromethyl)-4-oxo-1,4-dihydroquinoline-3-carboxylate; Ethyl 6-Trifluoromethyl-4-oxo-1,4-dihydroquinoline-3-carboxylate; 6-Trifluoromethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Ethyl Ester; 1,4-Dihydro-6-(trifluoromethyl)-4-oxoquinoline-3-carboxylic Acid Ethyl Ester; 6-CF3-DHQ Ethyl Ester; 6-Trifluoromethyl-4-hydroxyquinoline-3-carboxylic Acid Ethyl Ester; 71083-01-7
EINECS	Contact for details

Quality Control

Our 4-Oxo-6-Trifluoromethyl-1,4-Dihydro-Quinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.