Description

6-Fluoro-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid Ethyl Ester is a high-purity fluorinated quinolone derivative, serving as a critical advanced pharmaceutical intermediate. Its core value lies in enabling the synthesis of novel, potent antibacterial agents with enhanced activity profiles. This compound is essential for R&D and production teams in the pharmaceutical and fine chemical industries focused on developing next-generation quinolone antibiotics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel fluoroquinolone antibiotic APIs, such as ciprofloxacin and levofloxacin derivatives.
• Antimicrobial Research: Used in medicinal chemistry programs to develop new antibacterial compounds with improved efficacy against resistant strains.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization and the creation of complex heterocyclic libraries.
• Biochemical Studies: Employed as a reference standard or probe in studies investigating bacterial DNA gyrase and topoisomerase IV inhibition mechanisms.

Basic Information

Product Name	6-Fluoro-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	71083-00-6
Molecular Formula	C₁₂H₁₀FNO₃
Molecular Weight	235.21 g/mol
Synonyms	Ethyl 6-Fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate; 6-Fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic Acid Ethyl Ester; Ethyl 6-Fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate; 6-Fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; 6-Fluoro-4-hydroxyquinoline-3-carboxylic Acid Ethyl Ester; 6-Fluoro-4-oxoquinoline-3-carboxylic Acid Ethyl Ester; 71083-00-6
EINECS	Contact for details

Quality Control

Our 6-Fluoro-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. We provide material that meets exacting standards for pharmaceutical intermediate applications, with purity typically exceeding 98.0% (by HPLC). Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch to ensure traceability and compliance with your R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.