Description

8-Chloroquinoline-3-Carboxylic Acid is a high-purity, versatile quinoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials, where its specific chlorinated quinoline structure enables precise molecular modifications. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in developing molecules with potential anti-malarial, anti-cancer, or anti-inflammatory activities.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the quinoline core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating complex ligands used in catalytic systems and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs or conductive polymers, due to its electron-accepting quinoline structure.
• Chemical Biology Probes: Utilized to synthesize fluorescent tags or molecular probes for studying biological processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated quinoline carboxylic acids.

Basic Information

Product Name	8-Chloroquinoline-3-Carboxylic Acid
CAS No.	71082-54-7
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	3-Quinolinecarboxylic acid, 8-chloro-; 8-Chloro-3-quinolinecarboxylic acid; 8-Chloroquinoline-3-carboxylic acid; 8-Chloro-quinoline-3-carboxylic acid; 8-Cl-quinoline-3-COOH; 71082-54-7; 8-Chloro-3-quinoline carboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Chloroquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.