Description

7-(Trifluoromethyl)Quinoline-3-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced chemical synthesis. Its core value lies in the unique combination of the quinoline scaffold and the electron-withdrawing trifluoromethyl group, which is critical for modulating the physicochemical properties of target molecules. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, as well as by material scientists exploring advanced functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas like kinase inhibitors, antimicrobials, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group enhances bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, fluorescent dyes, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for designing molecular probes and tags for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	7-(Trifluoromethyl)Quinoline-3-Carboxylic Acid
CAS No.	71082-51-4
Molecular Formula	C11H6F3NO2
Molecular Weight	241.17 g/mol
Synonyms	3-Quinolinecarboxylic acid, 7-(trifluoromethyl)-; 7-Trifluoromethylquinoline-3-carboxylic acid; 7-(Trifluoromethyl)-3-quinolinecarboxylic acid; Quinoline-3-carboxylic acid, 7-(trifluoromethyl)-; 71082-51-4; 7-Trifluoromethyl-3-quinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 7-(Trifluoromethyl)Quinoline-3-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your application, whether for research or cGMP manufacturing. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting purity, identity, and impurity profiles. Our quality commitment aligns with industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.