Description

2-Chloro-N-(2,3-dihydroxypropyl)acetamide is a versatile chlorinated acetamide derivative featuring a reactive chloroacetyl group and a hydrophilic dihydroxypropyl moiety. This unique bifunctional structure makes it a valuable chemical intermediate for synthesizing more complex molecules, particularly in pharmaceutical and specialty chemical research. It is primarily sought by R&D chemists and process development scientists in the life sciences and fine chemical industries for applications requiring selective functionalization.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring chloroacetamide or glycerol-derived side chains.
• Bioconjugation Reagent: Used in the modification of peptides, proteins, and other biomolecules due to the reactivity of the chloroacetyl group with nucleophiles like thiols.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating functional polymers with hydroxyl groups, influencing hydrophilicity and reactivity.
• Agrochemical Synthesis: Intermediate in the production of herbicides, fungicides, or plant growth regulators that incorporate chloracetamide structures.
• Research & Development: A valuable tool compound in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Surface Modification: Used to introduce functional groups onto material surfaces for enhanced biocompatibility or specific chemical interactions.

Basic Information

Product Name	2-Chloro-N-(2,3-dihydroxypropyl)acetamide
CAS No.	71064-34-1
Molecular Formula	C5H10ClNO3
Molecular Weight	167.59 g/mol
Synonyms	N-(2,3-Dihydroxypropyl)-2-chloroacetamide; 2-Chloroacetamido-1,3-propanediol; 1,3-Dihydroxy-2-propylchloroacetamide; 2-Chloro-N-(2,3-dihydroxypropyl)ethanamide; Chloroacetic acid (2,3-dihydroxypropyl)amide; Glycerol 1-chloroacetamide; 3-Amino-1,2-propanediol chloroacetate (amide form)
EINECS	Contact for details

Quality Control

Our 2-Chloro-N-(2,3-dihydroxypropyl)acetamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.