Description

(S)-(+)-2-Amino-1-Phenylethanol Hydrochloride is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its value lies in its role as a precursor for a variety of active pharmaceutical ingredients (APIs) and fine chemicals, enabling the production of enantiomerically pure compounds. This product is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on creating chiral amines, β-amino alcohols, and related pharmacologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure APIs, particularly for cardiovascular and central nervous system drugs.
• Asymmetric Catalyst Ligand Precursor: Used to develop and manufacture chiral ligands for transition metal catalysis in stereoselective reactions.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex molecules in agrochemicals, flavors, and fragrances.
• Biochemical Research: Employed in the study of enzyme mechanisms and as a standard in chiral analytical method development (e.g., HPLC, CE).
• Resolution Agent: Can be utilized in the resolution of racemic mixtures of acids or other compounds due to its chiral amine functionality.

Basic Information

Product Name	(S)-(+)-2-Amino-1-Phenylethanol Hydrochloride
CAS No.	71025-82-6
Molecular Formula	C8H12ClNO
Molecular Weight	173.64 g/mol
Synonyms	(S)-(+)-2-Amino-1-phenylethanol HCl; (S)-2-Amino-2-phenylethanol Hydrochloride; (1S)-2-Amino-1-phenylethanol Hydrochloride; L-2-Amino-1-phenylethanol Hydrochloride; (S)-Phenylglycinol Hydrochloride; (S)-2-Phenyl-2-aminoethanol Hydrochloride; (S)-β-Amino-β-phenylethanol Hydrochloride; (S)-2-Amino-2-phenylethanol HCl
EINECS	Contact for details

Quality Control

Our (S)-(+)-2-Amino-1-Phenylethanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity (HPLC), specific rotation, and residual solvent levels are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0% ee
Specific Rotation [α]	+38.0° to +42.0° (c=1 in H2O)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.