Description

Dibenz(A,H)Anthracene-3,4-Diol 1,2-Oxide is a high-purity, polycyclic aromatic hydrocarbon (PAH) derivative and a specific metabolite of dibenz[a,h]anthracene. This compound is of significant value in advanced research and analytical chemistry, particularly for studying metabolic activation pathways and DNA adduct formation. It is primarily utilized by research institutions, pharmaceutical development labs, and environmental testing facilities requiring precise reference standards for toxicological and carcinogenicity studies.

Application

• Biochemical Research Standard: Used as a critical reference material in studies investigating the metabolic activation of polycyclic aromatic hydrocarbons (PAHs) and their role in carcinogenesis.
• Toxicology & Risk Assessment: Serves as a key analyte in developing and validating analytical methods (e.g., HPLC, GC-MS) for detecting and quantifying PAH metabolites in biological and environmental samples.
• DNA Adduct Studies: Employed in research to understand and characterize the covalent binding of activated PAH intermediates to DNA, which is a fundamental step in chemical carcinogenesis.
• Pharmaceutical Development: Used in early-stage discovery and safety assessment to evaluate the metabolic pathways and potential genotoxic risks of new chemical entities.
• Environmental Analysis: Acts as a high-purity calibration standard for monitoring PAH exposure and metabolic biomarkers in occupational health and environmental pollution studies.

Basic Information

Product Name	Dibenz(A,H)Anthracene-3,4-Diol 1,2-Oxide
CAS No.	70951-81-4
Molecular Formula	C22H14O3
Molecular Weight	326.35 g/mol
Synonyms	Dibenz[a,h]anthracene 3,4-diol 1,2-oxide; 3,4-Dihydroxy-3,4-dihydrodibenz[a,h]anthracene 1,2-oxide; Anti-DB[a,h]A-3,4-diol-1,2-oxide; DB[a,h]A-3,4-dihydrodiol-1,2-epoxide; PAH Metabolite Standard; Dibenzanthracene diol epoxide; 1,2-Epoxy-3,4-dihydroxy-1,2,3,4-tetrahydrodibenz[a,h]anthracene
EINECS	Contact for details

Quality Control

Our Dibenz(A,H)Anthracene-3,4-Diol 1,2-Oxide is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant industry standards for analytical reference materials to guarantee reliable and reproducible results in your laboratory.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (typically 15-25°C) in a dry, well-ventilated area. This compound is light-sensitive (store away from light). For long-term storage, consider storing under inert atmosphere at lower temperatures (e.g., -20°C) to maximize stability.

Specification

Item	Specification
Appearance	Off-white to light tan solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95% (Area %)
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.