Description

(R)-1,4-Benzodioxane-2-Carboxylic Acid is a high-purity chiral building block of significant importance in asymmetric synthesis. Its value lies in its utility as a key intermediate for constructing complex molecules with defined stereochemistry, which is critical for biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of enantiomerically pure pesticides and herbicides, where the specific stereochemistry can enhance efficacy and reduce environmental impact.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in stereoselective transformations.
• Fine Chemical and Specialty Chemical Production: Employed in the manufacture of complex fragrances, flavors, and other high-value fine chemicals requiring precise stereocontrol.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process chemistry optimization within pilot plants.

Basic Information

Product Name	(R)-1,4-Benzodioxane-2-Carboxylic Acid
CAS No.	70918-53-5
Molecular Formula	C9H8O4
Molecular Weight	180.16 g/mol
Synonyms	(R)-(+)-1,4-Benzodioxan-2-carboxylic acid; (2R)-2,3-Dihydro-1,4-benzodioxine-2-carboxylic acid; (R)-2,3-Dihydro-1,4-benzodioxine-2-carboxylic acid; (R)-1,4-Benzodioxan-2-carboxylic acid; (R)-2-Carboxy-2,3-dihydro-1,4-benzodioxin; (R)-Chroman-2-carboxylic acid derivative; (R)-Benzodioxane carboxylic acid; (R)-BDCA
EINECS	Contact for details

Quality Control

Our (R)-1,4-Benzodioxane-2-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are available upon request, providing full traceability and compliance documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.