Description

D-Ribose-1-13C is a stable isotope-labeled analog of the essential pentose sugar, D-ribose, where the carbon at the 1-position is the 13C isotope. This product is critical for advanced research and development requiring precise metabolic tracing and quantification in complex biological systems. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry (MS), and metabolic flux analysis.

Application

• Metabolic Pathway Tracing: Used as a tracer in in vitro and in vivo studies to elucidate nucleotide sugar metabolism, pentose phosphate pathway activity, and glycosylation processes.
• Quantitative NMR (qNMR): Serves as an internal standard for the accurate quantification of ribose-containing compounds and other metabolites in complex mixtures.
• Mass Spectrometry Standards: Employed as an internal standard in LC-MS and GC-MS workflows to improve the accuracy and precision of ribose and nucleoside measurements.
• Pharmaceutical R&D: Facilitates drug metabolism and pharmacokinetics (DMPK) studies for novel therapeutics targeting nucleotide synthesis or carbohydrate metabolism.
• Biochemical Research: Essential for studying enzyme kinetics, metabolic flux analysis (MFA), and the biosynthesis of RNA, ATP, and other critical biomolecules.
• Diagnostic Reagent Development: Used in the formulation of isotopic-labeled reagents for clinical diagnostics and biomarker discovery assays.

Basic Information

Product Name	D-Ribose-1-13C
CAS No.	70849-24-0
Molecular Formula	C413CH10O5
Molecular Weight	151.12 g/mol
Synonyms	1-13C-D-Ribose; (1-13C)Ribose; D-Ribose (1-13C); D-(-)-Ribose-1-13C; Ribose-1-13C; Aldopentose-1-13C; 1-Carbon-13 labeled D-ribose; 1-13C Isotopologue of D-Ribose
EINECS	Contact for details

Quality Control

Our D-Ribose-1-13C is manufactured under strict quality systems to ensure high isotopic and chemical purity for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters including isotopic enrichment (Atom % 13C), chemical purity, and specific analytical data from NMR and HPLC. We support compliance with relevant guidelines for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (Atom % 13C)	≥ 99%
Chemical Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	-20° to -23° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.