Description

cis-1,2-Cyclohexanedimethanamine is a versatile, chiral diamine building block of significant importance in advanced organic synthesis. Its rigid cyclohexane backbone and two primary amine functionalities make it a valuable precursor for creating complex molecular architectures with specific stereochemistry. This compound is particularly sought after by researchers and manufacturers in the pharmaceutical and specialty chemical sectors. It serves as a critical intermediate for developing chiral ligands, catalysts, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Catalyst & Ligand Synthesis: Used to construct sophisticated chiral ligands for transition metal catalysts, enabling enantioselective reactions in fine chemical production.
• Polymer & Resin Modification: Acts as a curing agent or cross-linking monomer in epoxy and polyurethane systems, imparting rigidity and chemical resistance to the final polymer.
• Corrosion Inhibitor Formulation: Incorporated into coatings and additives for metal surface treatment, providing excellent chelating and protective properties.
• Chelating Agent: Utilized in water treatment and metal extraction processes due to its ability to form stable complexes with various metal ions.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific stereochemistry.

Basic Information

Product Name	cis-1,2-Cyclohexanedimethanamine
CAS No.	70795-45-8
Molecular Formula	C8H18N2
Molecular Weight	142.24 g/mol
Synonyms	(1R,2S)-1,2-Bis(aminomethyl)cyclohexane; (1S,2R)-1,2-Bis(aminomethyl)cyclohexane; cis-1,2-Bis(aminomethyl)cyclohexane; (1R,2S)-Cyclohexane-1,2-dimethanamine; (1S,2R)-Cyclohexane-1,2-dimethanamine; cis-Cyclohexane-1,2-dimethanamine; 1,2-Cyclohexanedimethanamine, cis-; Rel-(1R,2S)-1,2-Bis(aminomethyl)cyclohexane
EINECS	Contact for details

Quality Control

Our cis-1,2-Cyclohexanedimethanamine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric excess, and impurity profiles. We support compliance with global regulatory frameworks, including REACH, and can provide material for GMP-related applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture and carbon dioxide, which can affect product quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC or Titration)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.