Description

(1R,11Ar)-3Aα,4,5,6-Tetrahydro-1β-(2-Propenyl)-3H-2β,5β-Methano-1H-Pyrrolo[3,4-I]Quinolizin-8(9H)-One is a complex, high-purity organic compound belonging to the pyrroloquinolizine class, serving as a critical advanced intermediate in modern synthetic chemistry. Its intricate polycyclic structure makes it a valuable building block for the development of novel pharmaceutical agents and bioactive molecules. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for use in process development, medicinal chemistry, and the synthesis of specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or alkaloid-based therapeutics.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry & Scale-Up: Serves as a critical intermediate in the pilot and commercial-scale synthesis of complex target molecules.
• Agrochemical Synthesis: Potential application as a building block for developing novel, high-efficacy crop protection agents with specific modes of action.
• Academic & Institutional Research: Employed in universities and R&D labs for methodological studies in asymmetric synthesis and heterocyclic chemistry.
• Fine Chemical Production: Used in the manufacture of specialty chemicals requiring a high degree of structural complexity and purity.

Basic Information

Product Name	(1R,11Ar)-3Aα,4,5,6-Tetrahydro-1β-(2-Propenyl)-3H-2β,5β-Methano-1H-Pyrrolo[3,4-I]Quinolizin-8(9H)-One
CAS No.	70711-82-9
Molecular Formula	C18H21NO2
Molecular Weight	283.37 g/mol
Synonyms	1H-Pyrrolo[3,4-i]quinolizin-8(9H)-one, 3a,4,5,6-tetrahydro-1-(2-propenyl)-, (1R,3aR,5R,11aR)-; (1R,3aR,5R,11aR)-3a,4,5,6-Tetrahydro-1-(2-propenyl)-1H-pyrrolo[3,4-i]quinolizin-8(9H)-one; 1-Allyl-1,2,3,4,5,6-hexahydro-2,5-methanopyrrolo[3,4-i]quinolizin-8-one; A complex pyrroloquinolizine alkaloid derivative.
EINECS	Contact for details

Quality Control

Our production of (1R,11Ar)-3Aα,4,5,6-Tetrahydro-1β-(2-Propenyl)-3H-2β,5β-Methano-1H-Pyrrolo[3,4-I]Quinolizin-8(9H)-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and structural confirmation via NMR and MS, to ensure it meets exacting research and development standards. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.