Description

trans-(1R,2R)-N,N'-Bismethyl-1,2-Cyclohexanediamine Hcl is a high-purity, chiral diamine derivative used as a critical building block and ligand in advanced chemical synthesis. Its value lies in its ability to impart stereochemical control in catalytic reactions and serve as a precursor for complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Asymmetric Catalysis Ligand: Used to construct chiral ligands for transition metal catalysts, enabling enantioselective hydrogenation, alkylation, and other critical transformations in fine chemical production.
• Agrochemical Synthesis: Employed in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators where specific stereochemistry is required for optimal activity.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing specialty polymers, resins, and advanced materials with tailored thermal and mechanical properties.
• Chelating Agent: Functions as a chelator for metal ions in analytical chemistry, catalysis, and in the formulation of certain industrial and laboratory reagents.
• Research & Development: A valuable tool for academic and industrial R&D in organic chemistry, medicinal chemistry, and process development for exploring new synthetic pathways.

Basic Information

Product Name	trans-(1R,2R)-N,N'-Bismethyl-1,2-Cyclohexanediamine Hcl
CAS No.	70708-33-7
Molecular Formula	C8H20N2 • 2HCl
Molecular Weight	225.17 g/mol (Free base: 156.26 g/mol)
Synonyms	(1R,2R)-N1,N2-Dimethylcyclohexane-1,2-diamine dihydrochloride; (1R,2R)-N,N'-Dimethyl-1,2-diaminocyclohexane Dihydrochloride; (1R,2R)-DACH-N,N'-dimethyl Dihydrochloride; trans-N,N'-Dimethyl-(1R,2R)-1,2-diaminocyclohexane Dihydrochloride; (R,R)-N,N'-Dimethyl-1,2-cyclohexanediamine Dihydrochloride; (1R,2R)-(-)-1,2-Diaminocyclohexane-N,N'-dimethyl Dihydrochloride; Chiral Diamine Ligand Precursor
EINECS	Contact for details

Quality Control

Our trans-(1R,2R)-N,N'-Bismethyl-1,2-Cyclohexanediamine Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chiral purity and chemical integrity, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.