Description

6-(2-Bromo-Acetyl)-3,4-Dihydro-1H-Quinolin-2-One is a high-purity, versatile brominated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its reactive bromoacetyl moiety, which enables efficient derivatization and serves as a key intermediate for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its quinolinone scaffold for biological activity.
• Organic Synthesis Building Block: Serves as a versatile electrophile in cross-coupling reactions, nucleophilic substitutions, and cyclization processes to create complex heterocycles.
• Material Science Research: Investigated as a monomer or precursor for the development of specialty polymers and advanced organic materials with specific optical or electronic properties.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	6-(2-Bromo-Acetyl)-3,4-Dihydro-1H-Quinolin-2-One
CAS No.	70639-82-6
Molecular Formula	C11H10BrNO2
Molecular Weight	268.11 g/mol
Synonyms	2-Bromo-1-(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)ethan-1-one; 6-Acetyl-2-bromo-3,4-dihydro-1H-quinolin-2-one; 6-(2-Bromoacetyl)-3,4-dihydro-2(1H)-quinolinone; 2-Bromo-1-(2-oxo-1,2,3,4-tetrahydro-6-quinolyl)ethanone; Bromoacetyl tetrahydroquinolinone; 70639-82-6; Quinolin-2-one, 3,4-dihydro-6-(2-bromoacetyl)-1H-
EINECS	Contact for details

Quality Control

Our 6-(2-Bromo-Acetyl)-3,4-Dihydro-1H-Quinolin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.