Description

1''-Methyl-3,4-Dihydrospiro[Chromene-2,4''-Piperidin]-4-Amine Hydrochloride is a high-purity organic compound belonging to the spirocyclic amine class, valued for its role as a sophisticated chemical intermediate. This compound matters for its structural complexity, which makes it a critical building block in the synthesis of advanced pharmaceutical candidates and fine chemicals. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic targets.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes in pilot plant and manufacturing settings.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and enzyme functions.
• Fine Chemical Synthesis: Employed in the production of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	1''-Methyl-3,4-Dihydrospiro[Chromene-2,4''-Piperidin]-4-Amine Hydrochloride
CAS No.	70505-90-7
Molecular Formula	C15H22N2O·HCl
Molecular Weight	282.81 g/mol (Free base: 246.35 g/mol)
Synonyms	1'-Methyl-3,4-dihydrospiro[chromene-2,4'-piperidin]-4-amine hydrochloride; 4-Amino-1'-methyl-3,4-dihydro-2H-spiro[chromene-2,4'-piperidine] hydrochloride; 1'-Methyl-3,4-dihydro-2H-spiro[chromene-2,4'-piperidin]-4-amine HCl; 1'-Methylspiro[chromane-2,4'-piperidin]-4-amine hydrochloride; 70505-90-7; Spiro[chromene-2,4'-piperidine]-4-amine, 1'-methyl-3,4-dihydro-, hydrochloride
EINECS	Contact for details

Quality Control

Our 1''-Methyl-3,4-Dihydrospiro[Chromene-2,4''-Piperidin]-4-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.