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D-Glucose, o-(n-Acetyl-.Alpha.-Neuraminosyl)-(23)-o-.Beta.-D-Galactopyranosyl-(14)-, Monoammonium Salt CAS NO 70472-21-8


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CAS No.:70472-21-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

D-Glucose, o-(n-Acetyl-.Alpha.-Neuraminosyl)-(23)-o-.Beta.-D-Galactopyranosyl-(14)-, Monoammonium Salt is a defined, high-purity carbohydrate derivative, specifically a sialylated trisaccharide in its ammonium salt form. This compound is of critical importance as a well-characterized reference standard and biochemical building block for advanced research and development. It is primarily needed by pharmaceutical, biotechnology, and diagnostic industries for applications in glycobiology, vaccine development, and the synthesis of complex glycoconjugates.

Application

  • Glycobiology Research: Used as a key intermediate or reference standard for studying sialic acid-containing glycans, cell-cell interactions, and receptor-ligand binding.
  • Pharmaceutical Development: Serves as a crucial starting material or precursor in the synthesis of complex carbohydrate-based drugs, vaccines, and therapeutic agents.
  • Diagnostic Reagent Manufacturing: Employed in the production of high-specificity diagnostic kits and assays that target sialylated antigens or biomarkers.
  • Enzymology Studies: Acts as a specific substrate for sialyltransferases, neuraminidases (sialidases), and other glycosyltransferases to study enzyme kinetics and inhibition.
  • Bioconjugation & Probe Synthesis: Utilized for the chemical or enzymatic synthesis of labeled probes (e.g., fluorescent, biotinylated) for imaging and detection applications.
  • Standards for Analytical Chemistry: Provides a certified reference material for HPLC, LC-MS, and other analytical methods to ensure accuracy in glycan analysis and quality control.

Basic Information

Product Name D-Glucose, o-(n-Acetyl-.Alpha.-Neuraminosyl)-(23)-o-.Beta.-D-Galactopyranosyl-(14)-, Monoammonium Salt
CAS No. 70472-21-8
Molecular Formula Contact for details
Molecular Weight Contact for details
Synonyms Ammonium 5-Acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosylonic acid-(2→3)-β-D-galactopyranosyl-(1→4)-D-glucopyranoside; α-Neu5Ac-(2→3)-β-D-Gal-(1→4)-D-Glc Ammonium Salt; Sialyl Lactose Ammonium Salt (Isomer); 3'-Sialyllactose Ammonium Salt; LST a Ammonium Salt; Neu5Acα2-3Galβ1-4Glc Ammonium Salt; Monosialyl Lacto-N-tetraose a (LSTa) Ammonium Salt
EINECS Contact for details

Quality Control

Our D-Glucose, o-(n-Acetyl-.Alpha.-Neuraminosyl)-(23)-o-.Beta.-D-Galactopyranosyl-(14)-, Monoammonium Salt is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques such as NMR, HPLC, and MS to confirm identity and purity, ensuring it meets the exacting standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) with lot-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white powder
Identification (NMR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 95% (Area %)
Water Content (KF) ≤ 5.0 %
Residual Solvents (GC) Meets ICH guidelines
Bacterial Endotoxins < 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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