Description

Ethyl 7-Chloro-6-Fluoro-4-Hydroxyquinoline-3-Carboxylate is a high-purity, multi-functional quinoline derivative that serves as a critical advanced pharmaceutical intermediate. Its value lies in its precise molecular structure, which is engineered for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the fluoroquinolone antibiotic class. This compound is essential for research institutions and manufacturers in the pharmaceutical and fine chemical sectors who require a reliable, high-quality building block for drug discovery and development processes.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of novel fluoroquinolone antibiotics and other therapeutic agents.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex heterocyclic compounds in custom synthesis projects.
• API Manufacturing: Integrated into scaled-up GMP processes for the commercial production of active pharmaceutical ingredients.

Basic Information

Product Name	Ethyl 7-Chloro-6-Fluoro-4-Hydroxyquinoline-3-Carboxylate
CAS No.	70458-93-4
Molecular Formula	C12H9ClFNO3
Molecular Weight	269.66 g/mol
Synonyms	7-Chloro-6-fluoro-4-hydroxyquinoline-3-carboxylic acid ethyl ester; Ethyl 7-chloro-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate; 4-Hydroxy-7-chloro-6-fluoroquinoline-3-carboxylic acid ethyl ester; 3-Quinolinecarboxylic acid, 7-chloro-6-fluoro-4-hydroxy-, ethyl ester; 1,4-Dihydro-7-chloro-6-fluoro-4-oxo-3-quinolinecarboxylic acid ethyl ester; 7-Chloro-6-fluoro-4-hydroxy-3-quinolinecarboxylic acid ethyl ester; 70458-93-4
EINECS	Contact for details

Quality Control

Our Ethyl 7-Chloro-6-Fluoro-4-Hydroxyquinoline-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high standards, from research to GMP-grade manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.