Description

3-Quinolinecarboxylic Acid, 6-Bromo-7-Chloro-1-Ethyl-1,4-Dihydro-4-Oxo- is a high-purity, multi-halogenated quinoline derivative serving as a critical advanced pharmaceutical intermediate. Its complex halogenated structure makes it a valuable building block for synthesizing novel active pharmaceutical ingredients (APIs) with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating next-generation quinolone-based therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinolone and fluoroquinolone antibiotic candidates.
• Agrochemical Research: Used in developing new crop protection agents and pesticides due to its bioactive quinoline core.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing complex heterocyclic compounds for material science and medicinal chemistry.
• Biochemical Research: Serves as a standard or reference compound in biochemical assays and pharmacological studies targeting bacterial enzymes.
• API Development: Integral in the research and scale-up processes for new Active Pharmaceutical Ingredients under GMP conditions.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 6-Bromo-7-Chloro-1-Ethyl-1,4-Dihydro-4-Oxo-
CAS No.	70458-86-5
Molecular Formula	C₁₂H₉BrClNO₃
Molecular Weight	330.56 g/mol
Synonyms	6-Bromo-7-chloro-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid; 1-Ethyl-6-bromo-7-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 6-Bromo-7-chloro-1-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; ABT-719 intermediate; Quinolone carboxylic acid derivative; Bromochloroethyloxoquinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid, 6-Bromo-7-Chloro-1-Ethyl-1,4-Dihydro-4-Oxo- is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical R&D. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry guidelines to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.