Description

2,2',4,5-Tetrachlorobiphenyl is a specific congener of polychlorinated biphenyls (PCBs), a well-studied class of synthetic organic chemicals. This compound is primarily utilized as a critical analytical reference standard for environmental monitoring, toxicological research, and regulatory compliance testing. It is essential for laboratories and research institutions focused on persistent organic pollutant (POP) analysis, method development, and quality control in industries such as environmental consulting, food safety, and industrial hygiene.

Application

• Environmental Analysis Reference Standard: Used for the calibration of GC/MS and HPLC systems in the quantification of PCB congeners in soil, water, sediment, and air samples.
• Toxicological and Biomedical Research: Serves as a pure congener for studying the metabolism, pharmacokinetics, and specific toxic effects (e.g., endocrine disruption) of PCBs.
• Food and Feed Safety Testing: Employed as a certified reference material (CRM) to ensure accurate detection and quantification of PCB contaminants in the food chain.
• Regulatory Compliance and Proficiency Testing: Essential for laboratories to validate analytical methods and demonstrate competency in accordance with EPA, EU, and other international regulations (e.g., Stockholm Convention).
• Waste and Material Analysis: Used to identify and quantify PCB content in industrial wastes, transformer oils, and other legacy materials for proper disposal classification.
• Method Development and Validation: Provides a high-purity benchmark for developing new analytical techniques for persistent organic pollutant detection.

Basic Information

Product Name	2,2',4,5-Tetrachlorobiphenyl
CAS No.	70362-47-9
Molecular Formula	C₁₂H₆Cl₄
Molecular Weight	291.99 g/mol
Synonyms	PCB 49; 2,2',4,5-Polychlorinated Biphenyl; 2,2',4,5-TCB; Biphenyl, 2,2',4,5-tetrachloro-; 2,2',4,5-Tetrachloro-1,1'-biphenyl; 2,2',4,5-Tetrachlorodiphenyl; IUPAC: 1,2,4-Trichloro-5-(2-chlorophenyl)benzene (alternative numbering).
EINECS	Contact for details

Quality Control

Our high-purity 2,2',4,5-Tetrachlorobiphenyl is manufactured and handled under strict quality protocols to ensure identity, purity, and stability. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results from advanced chromatographic and spectroscopic methods. We support compliance with relevant standards for reference materials, and specifications can be tailored for specific research or calibration programs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). For long-term stability, storage under inert atmosphere (e.g., argon or nitrogen) is recommended. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR / NMR)	Conforms to structure
Assay (HPLC / GC)	≥ 98.0% (Area Percent)
Related Substances (HPLC)	Total other PCB congeners ≤ 1.0%
Solubility	Soluble in common organic solvents (e.g., hexane, acetone, toluene)
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.